BAR-502 | B1965

BAR-502 is a dual FXR (farnesoid X receptor) and GPBAR1 (G protein-coupled bile acid-activated receptor) agonist. BAR-502 promotes browning of white adipose tissue and reverses liver steatosis and fibrosis. BAR502 protects against liver damage caused by HFD by promoting the browning of adipose tissue.

BAR-502 is a dual FXR (farnesoid X receptor) and GPBAR1 (G protein-coupled bile acid-activated receptor) agonist. BAR-502 promotes browning of white adipose tissue and reverses liver steatosis and fibrosis. BAR502 protects against liver damage caused by HFD by promoting the browning of adipose tissue.

B1965 | BAR-502 DataSheet

Alternate Name/Synonyms: (3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-((R)-4-hydroxybutan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol; BAR502

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1612191-86-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₄₄O₃

Molecular Weight: 392.62

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A dual FXR (farnesoid X receptor) and GPBAR1 (G protein-coupled bile acid-activated receptor) agonist

MDL Number: N/A

PubChem CID: 129317950

SMILES: CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCO)C)C)O

InChi: InChI=1S/C25H44O3/c1-5-17-21-14-16(27)8-11-25(21,4)20-9-12-24(3)18(15(2)10-13-26)6-7-19(24)22(20)23(17)28/h15-23,26-28H,5-14H2,1-4H3/t15?,16?,17?,18-,19+,20-,21+,22+,23?,24-,25-/m1/s1

InChi Key: HYCMOIGNYNCMRH-BNVZFTBUSA-N