BATF3 Antibody | 7939

BATF3 Antibody | 7939 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: BATF3 antibody was raised against a 16 amino acid peptide near the amino terminus of human BATF3.
The immunogen is located within the first 50 amino acids of BATF3.

Research Area: Immunology, Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: BATF3 body can be used for detection of BATF3 by Western blot at 0.5 μg/ml. Antibody can also be used for Immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 14 kDa
Observed: 17 kDa

Validation: N/A

Isoform: N/A

Purification: BATF3 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: BATF3 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: BATF3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Basic leucine zipper transcriptional factor ATF-like 3, SNFT, JDP1, JUNDM1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1, 2) . BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3, 4) .