BATF3 Antibody (Center) [APR33351G]

BATF3 Antibody (Center) [APR33351G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This BATF3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 58-89 amino acids from the Central region of human BATF3.

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12087103}

Molecular Weight: 14468

Clone: Polyclonal

Gene Name: BATF3

Gene ID: 55509

Function: AP-1 family transcription factor that controls the differentiation of CD8 (+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha (+) classical dendritic cells (cDCs) and related CD103 (+) dendritic cells that cross- present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity) . Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT, BATF3, SNFT