BAY-8002 | B2564

BAY-8002 is a potent dual MCT1/2 (Monocarboxylate Transporter ½) inhibitor. Inhibits cellular SNARF-5 fluorescence change (IC₅₀ = 85 nM) in MCT1-expressing DLD-1 cells. Arrests growth and increases intratumor lactate levels of Raji tumor xenografts in mice.

BAY-8002 is a potent dual MCT1/2 (Monocarboxylate Transporter ½) inhibitor. Inhibits cellular SNARF-5 fluorescence change (IC₅₀ = 85 nM) in MCT1-expressing DLD-1 cells. Arrests growth and increases intratumor lactate levels of Raji tumor xenografts in mice.

B2564 | BAY-8002 DataSheet

Alternate Name/Synonyms: BAY8002, 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid, BAY 8002

Appearance: White solid

Formulation:

CAS Number: 724440-27-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₄ClNO₅S

Molecular Weight: 415.85

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >80 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Potent dual MCT1/2 inhibitor

MDL Number:

PubChem CID: 992293

SMILES: OC(C1=C(C=CC=C1)NC(C2=C(C=CC(S(=O)(C3=CC=CC=C3)=O)=C2)Cl)=O)=O

InChi: InChI=1S/C20H14ClNO5S/c21-17-11-10-14(28(26,27)13-6-2-1-3-7-13)12-16(17)19(23)22-18-9-5-4-8-15(18)20(24)25/h1-12H,(H,22,23)(H,24,25)

InChi Key: CLAUJSRBKSRTGQ-UHFFFAOYSA-N