BAY-876 | B1572

BAY-876 is a highly selective GLUT1 inhibitor (IC₅₀ = 2 mM). Displays good metabolic stability in vitro and high oral bioavailability in vivo.

BAY-876 is a highly selective GLUT1 inhibitor (IC₅₀ = 2 mM). Displays good metabolic stability in vitro and high oral bioavailability in vivo.

B1572 | BAY-876 DataSheet

Alternate Name/Synonyms: N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-Quinolinedicarboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1799753-84-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₄H₁₆F₄N₆O₂

Molecular Weight: 496.42

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly selective GLUT1 inhibitor

MDL Number: N/A

PubChem CID: 118191391

SMILES: CC1=C(C(=NN1CC2=CC=C(C=C2)C#N)C(F)(F)F)NC(=O)C3=CC(=NC4=C3C=CC(=C4)F)C(=O)N

InChi: InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36)

InChi Key: BKLJDIJJOOQUFG-UHFFFAOYSA-N