BBC3 Polyclonal Antibody | E-AB-40332

BBC3 Polyclonal Antibody | E-AB-40332 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: BBC 3, Bbc3, BBC3, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1

Application: IHC

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Bcl-2-binding component 3 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: IHC 1:100-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A