BBS2 Polyclonal Antibody | E-AB-62011

BBS2 Polyclonal Antibody | E-AB-62011 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: BBS2, BBS, RP74

Application: WB

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Neuroscience

Background: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human BBS2 (NP_114091.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 79 kDa

Molecular Weight(Observed): 100 kDa