BC-1618 | B3333

BC-1618 is a potent Fbxo48 inhibitory compound that stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). Fbxo48 and was much more potent than metformin in increasing Ampk function. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.

BC-1618 is a potent Fbxo48 inhibitory compound that stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). Fbxo48 and was much more potent than metformin in increasing Ampk function. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.

B3333 | BC-1618 DataSheet

Alternate Name/Synonyms: BC1618 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-

Appearance: Solid

Formulation:

CAS Number: 2222094-18-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₄F₃NO₂

Molecular Weight: 415.45

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An orally active Fbxo48 inhibitor

MDL Number:

PubChem CID:

SMILES: OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3

InChi: InChI=1S/C24H24F3NO2/c25-24(26,27)21-11-13-23(14-12-21)30-18-22(29)17-28(15-19-7-3-1-4-8-19)16-20-9-5-2-6-10-20/h1-14,22,29H,15-18H2

InChi Key: LGTYABNNHILKHF-UHFFFAOYSA-N