BCAS2 Antibody | XW-7054

BCAS2 Antibody | XW-7054 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat, Frog

Homology: N/A

Immunogen: 1-225

Research Area: Apoptosis

Tested Application: WB

Application: BCAS2 antibody can be used for the detection of BCAS2 by Western blot, may also work for IHC and ICC.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 26.1 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Antigen affinity-purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: BCAS2 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: DAM1, Pre-mRNA-splicing factor SPF27, Breast carcinoma-amplified sequence 2, DAM1, SPF27, Snt309, BCAS2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: BCL2-antagonist of cell death protein; BCL2-binding protein; BCL2-binding component 6; BCL-X/BCL-2 binding protein. This protein is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. It positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing the death repressor activity. Proapoptotic activity of protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, and protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of the gene results in two transcript variants which encode the same isoform.