BCI-121 | B3251

BCI-121 is a substrate-competitive SMYD3 inhibitor that reduces nuclear histone H3 lys4 di- and tri-methylation level, downregulates known SMYD3 target genes transcription, and selectively affects SMYD3-dependent proliferation of cancer cultures with little antiproliferation efficacy toward low SMYD3-expressing cancer cells.

BCI-121 is a substrate-competitive SMYD3 inhibitor that reduces nuclear histone H3 lys4 di- and tri-methylation level, downregulates known SMYD3 target genes transcription, and selectively affects SMYD3-dependent proliferation of cancer cultures with little antiproliferation efficacy toward low SMYD3-expressing cancer cells.

B3251 | BCI-121 DataSheet

Alternate Name/Synonyms: BCI121 4-(Aminocarbonyl)-N-(4-bromophenyl)-1-piperidineacetamide

Appearance: White to off-white solid

Formulation:

CAS Number: 432529-82-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₈BrN₃O₂

Molecular Weight: 340.22

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A substrate-competitive SMYD3 inhibitor

MDL Number:

PubChem CID: 795875

SMILES: C1CN(CCC1C(=O)N)CC(=O)NC2=CC=C(C=C2)Br

InChi: InChI=1S/C14H18BrN3O2/c15-11-1-3-12(4-2-11)17-13(19)9-18-7-5-10(6-8-18)14(16)20/h1-4,10H,5-9H2,(H2,16,20)(H,17,19)

InChi Key: KSUYPIXCRPCPGF-UHFFFAOYSA-N