Bcl-2 polyclonal Antibody | BS90126

Bcl-2 polyclonal Antibody | BS90126 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC FC

Application Range: WB:1:500 ICC:1:200 IHC:1:200 FC:1:50-1:100

Background: Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and autoimmunity. It is also a cause of resistance to cancer treatments. Antibodies to Bcl-2 can be used with immunohistochemistry to identify cells containing the antigen. In healthy tissue, these antibodies will react with B-cells in the mantle zone, as well as some T-cells. However, there is a considerable increase in positive cells in follicular lymphoma, as well as many other forms of cancer. In some cases, the presence or absence of Bcl-2 staining in biopsies may be significant for the patient's prognosis or likelihood of relapse.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Bcl-2 polyclonal Antibody detects endogenous levels of Bcl-2 protein.

Molecular Weight: 26kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BCL2, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, PPP1R50, Protein phosphatase 1, regulatory subunit 50,

Immunogen: Synthetic peptide (KLH-coupled) within human Bcl-2 aa 20-80.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: