Bcl-7a (N62) polyclonal Antibody | BS9274

Bcl-7a (N62) polyclonal Antibody | BS9274 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL) . Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Bcl-7a (N62) polyclonal Antibody detects endogenous levels of Bcl-7a protein.

Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: B cell CLL/lymphoma 7; B cell CLL/lymphoma 7 protein family member A; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; BCL 7; BCL7; bcl7a; BCL7A

Immunogen: Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: