BCL10 Polyclonal Antibody | E-AB-10997

BCL10 Polyclonal Antibody | E-AB-10997 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AI132454, B cell CLL/lymphoma 10, B cell lymphoma/leukemia10, B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, B-cell lymphoma/leukemia 10, Bcl 10, Bcl-10, Bcl10, BCL10, c E10, c-E10, C81403, CARD containing apoptotic signaling protein, CARD containing molecule enhancing NF kappa B, CARD containing molecule enhancing NF kB, CARD containing molecule enhancing NF-kB, CARD containing molecule enhancing NFkB, CARD containing proapoptotic protein, CARD like apoptotic protein, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, Caspase recruiting domain containing protein, caspase-recruiting domain-containing protein, cCARMEN, cE 10, cE10, CED 3/ICH 1 prodomain homologous E10 like regulator, CED-3/ICH-1 prodomain homologous E10-like regulator, CED3/ICH1 prodomain homologous E10 like regulator, Cellular E10, Cellular homolog of vCARMEN, Cellular-E10, CIPER, CLAP, hCLAP, Mammalian CARD containing adapter molecule E10, Mammalian CARD-containing adapter molecule E10, mE 10, mE10, R-RCD1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human BCL10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 26 kDa

Molecular Weight(Observed): N/A