BCL2 Antibody | 18-575

BCL2 Antibody | 18-575 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human BCL2

Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Tested Application: WB, IHC, IP, Flow

Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
IP: 1:20 - 1:50
Flow: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: U-937

Positive Control 3: MCF7

Positive Control 4: Mouse liver

Positive Control 5: Rat brain

Positive Control 6: N/A

Molecular Weight: Observed: 26kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.