Bcl2 Antibody | 18-834

Bcl2 Antibody | 18-834 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 81-131 of human Bcl2 (NP_000624.2) .

Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Tested Application: WB, IF, IP

Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:100
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Raji

Positive Control 2: HL-60

Positive Control 3: U-937

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 27kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.