BCL2 monoclonal Antibody | MB9086

BCL2 monoclonal Antibody | MB9086 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB IHC

Application Range: WB:1:500-1:1,000 IHC:1:500-1:1,000

Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: BCL2 monoclonal Antibody detects endogenous levels of BCL2 protein.

Molecular Weight: 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BCL2, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, PPP1R50, Protein phosphatase 1, regulatory subunit 50,

Immunogen: Synthetic peptide within human BCL2 35-60 aa.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: