BCL2 Protein, Human Recombinant | P1627

BCL-2 was the first anti-death gene discovered with far reaching implications in tumor biology. It regulates cell death by either inhibiting (anti-apoptotic) or inducing (pro-apoptotic) apoptosis. The BCL-2 protein is the founding member of the BCL-2 family of apoptosis regulators and was the first apoptosis modulator to be associated with cancer. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL-2 regulates cell death by controlling the mitochondrial membrane permeability.

P1627 | BCL2 Protein, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Protein phosphatase 1,Regulatory subunit 50,BCL - XL,BCL2 apoptosis regulator,B - cell CLL/lymphoma 2,PPP1R50

Alternates names: Protein phosphatase 1,Regulatory subunit 50,BCL - XL,BCL2 apoptosis regulator,B - cell CLL/lymphoma 2,PPP1R50

Taglines: Human Recombinant protein

NCBI Gene ID #: 596

NCBI Gene Symbol: 231632

Gene Source: Human

Accession #: NP_000624.2, P10415

Recombinant: TRUE

Source: E.coli

Purity by SDS-PAGE: ≥ 95% by SDS-PAGE

Assay:

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Unit Definition:

Molecular Weight: 25 kDa

Concentration:

Appearance: Liquid

Physical form description:

Reconstitution Instructions:

Amino acid sequence: The target protein is expressed with sequence (Ala2-Asp211) of human BCL2.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans