BCL2L14 polyclonal Antibody | BS8249

BCL2L14 polyclonal Antibody | BS8249 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BCL2L14 polyclonal Antibody detects endogenous levels of BCL2L14 protein.

Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Apoptosis facilitator Bcl-2-like protein 14; Bcl2-L-14; Apoptosis regulator Bcl-G; BCL2L14; BCLG

Immunogen: Recombinant full length Human BCL2L14.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: