BCL2L2 Polyclonal Antibody | E-AB-53595

BCL2L2 Polyclonal Antibody | E-AB-53595 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Apoptosis regulator BCL W, Apoptosis regulator Bcl-W, B2CL2, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, BCL W, Bcl-2-like protein 2, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, Bcl2-L-2, Bcl2l2, BCLW, KIAA0271, PPP1R51, Protein phosphatase 1 regulatory subunit 51

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human BCL2L2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 21 kDa

Molecular Weight(Observed): Refer to figures