Benserazide hydrochloride | B2963

Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. It causes an increase in the amount of L-DOPA reaching the central nervous system and so reduces the required dose. It is often combined with L-DOPA in patients with Parkinson’s disease.

Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. It causes an increase in the amount of L-DOPA reaching the central nervous system and so reduces the required dose. It is often combined with L-DOPA in patients with Parkinson’s disease.

B2963 | Benserazide hydrochloride DataSheet

Alternate Name/Synonyms: DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide Hydrochloride; 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride; 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide, hydrochloride

Appearance: A crystalline solid

Formulation:

CAS Number: 14919-77-8

Structure Available?: True

Peptide sequence:

Salt Form: true

Molecular Formula: C₁₀H₁₆ClN₃O₅

Molecular Weight: 293.7

Cell-Permeable?: True

Purity: ≥95%

Solubilities: ~16 mg/ml in in DMSO, ~20 mg/ml in DMF in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An inhibitor of aromatic L-amino acid decarboxylase (DOPA decarboxylase)

MDL Number: MFCD00078571

PubChem CID: 26964

SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

InChi: InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

InChi Key: ULFCBIUXQQYDEI-UHFFFAOYSA-N