beta 2 Microglobulin Antibody, KO Validated | 14-403

beta 2 Microglobulin Antibody, KO Validated | 14-403 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1) .

Research Area: Cancer

Tested Application: WB, IHC, IP

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: COS7

Positive Control 3: HeLa

Positive Control 4: K-562

Positive Control 5: Mouse liver

Positive Control 6: Mouse spleen

Molecular Weight: Observed: 12kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: B2M Antibody: Beta-2-microglobulin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.