beta2-Microglobulin Antibody [F21-21] | 99-282

beta2-Microglobulin Antibody [F21-21] | 99-282 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Chicken, Turkey

Homology: N/A

Immunogen: Affinity purified chicken MHC-I molecules

Research Area: Cancer, Immunology

Tested Application: IHC-Fr, ICC, Flow, Separation

Application: beta2-Microglobulin Antibody [F21-21] for use in flow cytometry, immunocytochemistry, western blotting, immunoprecipitation, and purification assays.

Specificiy: beta2-Microglobulin

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [F21-21]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: MHC Class I, B-F

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes which are usually cytotoxic T cells. The monoclonal antibody F21-21 also reacts with turkey beta2-microglobulin.