Bexarotene | 1575

Bexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer.

Bexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. Acts as an antineoplastic agent.

1575 | Bexarotene DataSheet

Alternate Name/Synonyms: Targretin, LGD-1069, LG-1069, LG10069, SR-11247

Appearance: Off-white solid

Formulation: N/A

CAS Number: 153559-49-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₈O₂

Molecular Weight: 348.48

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO

Handling: Protect from light and air

Country of Origin: USA

Tag Line: An antineoplastic agent

MDL Number: MFCD00932428

PubChem CID: 82146

SMILES: CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C

InChi: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)

InChi Key: NAVMQTYZDKMPEU-UHFFFAOYSA-N