Bexgliflozin (EGT1442) | B1929

Bexagliflozin is a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC₅₀ values of 5.6 µM and 2 nM for human SGLT1 and SGLT2, respectively. Bexagliflozin dose-dependently reduces HbA(1c) and blood glucose concentration without affecting body mass or insulin level.

Bexagliflozin is a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC₅₀ values of 5.6 µM and 2 nM for human SGLT1 and SGLT2, respectively. Bexagliflozin dose-dependently reduces HbA(1c) and blood glucose concentration without affecting body mass or insulin level.

B1929 | Bexgliflozin (EGT1442) DataSheet

Alternate Name/Synonyms: (3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; EGT1442; THR1442

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1118567-05-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₉ClO₇

Molecular Weight: 464.94

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent sodium-glucose cotransporter 2 (SGLT2) inhibitor

MDL Number: N/A

PubChem CID: 25195624

SMILES: C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl

InChi: InChI=1S/C24H29ClO7/c25-19-8-3-15(24-23(29)22(28)21(27)20(13-26)32-24)12-16(19)11-14-1-4-17(5-2-14)30-9-10-31-18-6-7-18/h1-5,8,12,18,20-24,26-29H,6-7,9-11,13H2/t20-,21-,22+,23-,24+/m1/s1

InChi Key: BTCRKOKVYTVOLU-SJSRKZJXSA-N