BF2649 hydrochloride | B2279

BF2649 is a potent, cell-permeable and selective histamine H3 receptor inverse agonist (EC₅₀ = 1.5 nM, Ki = 0.16 nM). BF2649 displays nootropic effects in cognitive disorders; reduces locomotor hyperactivity induced by methamphetamine.

BF2649 is a potent, cell-permeable and selective histamine H3 receptor inverse agonist (EC₅₀ = 1.5 nM, Ki = 0.16 nM). BF2649 displays nootropic effects in cognitive disorders; reduces locomotor hyperactivity induced by methamphetamine.

B2279 | BF2649 hydrochloride DataSheet

Alternate Name/Synonyms: 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;hydrochloride; Pitolisant

Appearance: Off-white solid

Formulation: N/A

CAS Number: 903576-44-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₇Cl₂NO

Molecular Weight: 332.31

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml) or H2O (>30 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent, cell-permeable and selective histamine H3 receptor inverse agonist

MDL Number: MFCD09970745

PubChem CID: 11551689

SMILES: C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.Cl

InChi: InChI=1S/C17H26ClNO.ClH/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19;/h7-10H,1-6,11-15H2;1H

InChi Key: XLFKECRRMPOAQS-UHFFFAOYSA-N