BFSP2 Antibody | 14-769

BFSP2 Antibody | 14-769 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 116-415 of human BFSP2 (NP_003562.1) .

Research Area: Cell Cycle, Neuroscience

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Mouse eye

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 46kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CP47, CP49, CTRCT12, LIFL-L, PHAKOSIN, phakinin, 49 kDa cytoskeletal protein, beaded filament protein CP49, beaded filament structural protein 2, phakinin, bfps2, Cytoskeletal protein, 49-kD, lens fiber cell beaded filament protein CP 47, lens fiber cell beaded filament protein CP 49, lens intermediate filament-like light

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin) , and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF) . Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.