BGT226 | B1719

BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively.

BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively.

B1719 | BGT226 DataSheet

Alternate Name/Synonyms: BGT226; BGT 226; BGT-226; NVP-BGT226; NVPBGT226; NVP BGT226; (Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one; 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt

Appearance: Solid

Formulation: N/A

CAS Number: 1245537-68-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₂H₂₉F₃N₆O₆

Molecular Weight: 650.6

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel inhibitor of class I PI3K/mTOR

MDL Number: MFCD22124895

PubChem CID: 57336745

SMILES: CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=CC(=O)O)C(=O)O

InChi: InChI=1S/C28H25F3N6O2.C4H4O4/c1-35-24-16-33-22-6-3-17(18-4-8-25(39-2)34-15-18)13-20(22)26(24)37(27(35)38)19-5-7-23(21(14-19)28(29,30)31)36-11-9-32-10-12-36;5-3(6)1-2-4(7)8/h3-8,13-16,32H,9-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChi Key: YUXMAKUNSXIEKN-BTJKTKAUSA-N