Bi-Phospho-LLGL1/2 (S653/S649) Antibody [APR04976G]

Bi-Phospho-LLGL1/2 (S653/S649) Antibody [APR04976G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LLGL1/2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S645/S649 of human LLGL1/2.

Cellular Localisation: Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell- cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells

Molecular Weight: 113448

Clone: Polyclonal

Gene Name: LLGL2

Gene ID: 3993

Function: Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par- 6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Lethal (2) giant larvae protein homolog 2, HGL, LLGL2