Additional Information
Short Description: |
EGFR, HER2 kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
Afatinib, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
850140-72-6 |
Molecular Formula: |
C24H25ClFN5O3 |
Molecular Weight: |
485,9 |
Source: |
Synthetic |
Purity: |
>99% |
Solubility: |
Soluble in DMSO at 200 mg/ml; in ethanol at 25 mg/ml |
Appearance: |
Crystalline solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 |
InChI: |
InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1 |
InChIKey: |
ULXXDDBFHOBEHA-CWDCEQMOSA-N |
Field of Use: |
For in vitro research use only. |
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