BID, Human Recombinant | P1571

BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E. coli and purified by using conventional chromatography techniques.

P1571 | BID, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: BH3-interacting domain death agonist, p22 BID, p11 BID

Alternates names: BH3-interacting domain death agonist, p22 BID, p11 BID

Taglines: Pro-apoptotic Bcl-2 protein

NCBI Gene ID #: 637

NCBI Gene Symbol: BID

Gene Source: Human

Accession #: P55957

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: >95%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 21.9 kDa

Concentration:

Appearance: Sterile Filtered colorless solution

Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Reconstitution Instructions:

Amino acid sequence: aa 1-195

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans