BIRC3 monoclonal Antibody | MB0129

BIRC3 monoclonal Antibody | MB0129 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Monkey

Application: WB

Application Range: WB: 1:1000

Background: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases.The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione,a potent inducer of free radicals.It contains 3 baculovirus IAP repeats and a ring finger domain.Transcript variants encoding the same isoform have been identified.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BIRC3 mAb detects endogenous levels of BIRC3 protein.

Molecular Weight: Predicted band size:68KDa Observed band size:72KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Baculoviral IAP repeat-containing protein 3; Apoptosis inhibitor 2; API2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; IAP-1; hIAP-1; hIAP1; RING finger protein 49; TNFR2-TRAF-signaling complex protein 1; BIRC3; API2; IAP1; MIHC; RNF49

Immunogen: Recombinant full length Human BIRC3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: