BLNK Polyclonal Antibody | E-AB-13091

BLNK Polyclonal Antibody | E-AB-13091 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AGM4, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell adaptor containing SH2 domain, B cell linker, B cell linker protein, B cell-specific adaptor protein, B-cell activation, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, Bca, BLNK, BLNK s, BLNK, Cytoplasmic adapter protein, Ly 57, Ly57, Lymphocyte antigen 57, Lyw 57, Lyw57, MGC111051, SH2 domain-containing leukocyte protein, 65-KD, SLP 65, SLP-65, SLP65, Src homology [SH2] domain-containing leukocyte protein of 65 kD, Src homology 2 domain containing leukocyte protein of 65 kDa, Src homology 2 domain-containing leukocyte protein of 65 kDa

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology, Signal Transduction

Background: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human BLNK

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A