BMP-12/GDF-7, human recombinant | 4572

BMPs (bone morphogenetic proteins) belong to the TGF- superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.

4572 | BMP-12/GDF-7 human recombinant DataSheet

Biomolecule/Target: BMP-12/GDF-7

Synonyms: bone morphogenetic protein 12, BMP12, BMP 12

Alternates names: Fatty acid-binding protein 5, Fatty acid-binding protein epidermal, Epidermal-type fatty acid-binding protein, E-FABP, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, PA-FABP

Taglines: A protein with functions in regulating inflammatory and apoptotic pathways

NCBI Gene ID #: 2171

NCBI Gene Symbol: FABP5

Gene Source: Human

Accession #: Q01469

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Test in process

Results: 0.2 – 2.5 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 16 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A