BMP-3b/GDF-10, human recombinant | 7303

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.

7303 | BMP-3b/GDF-10 human recombinant DataSheet

Biomolecule/Target: GDF10

Synonyms: BMP-3b, BMP3B, BIP, Growth differentiation factor 10

Alternates names: BMP-3b, BMP3B, BIP, Growth differentiation factor 10

Taglines: Has multiple roles in skeletal morphogenesis

NCBI Gene ID #: 1514

NCBI Gene Symbol: CTSL1

Gene Source: Human

Accession #: P07711

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 microgram of protein

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 12.5 kDa (111 aa, 369-478 aa), confirmed by MALDI-TOF.

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 10 mM sodium citrate (pH 3.5) containing 10% glycerol

Reconstitution Instructions: N/A

Amino acid sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R