BMP-4 Antibody | 5674R

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented thro?ghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), s?ggesting that BMP-4 may play a role in activation of the Smad pathway.

5674R | BMP-4 Antibody DataSheet

Antibody Target: BMP-4

Target Alternative Name: BMP4, BMP-4, BMP 4, bone morphogenetic protein 4, BMP2B, BMP2B1

Tag Line:

Category: BMP

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse, rat, chicken, rabbit

Immunogen Sequence: Synthetic peptide surrounding amino acid 395 of human BMP-4

Accession #: P12644

Gene ID: 652

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin

Purification: Affinity purified

Application: Western blot, Immunohistochemistry

Positive Control:

Application And Usages: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified