BMP-6, human recombinant | 4911

BMPs (bone morphogenetic proteins) belong to the TGF- superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-6 produced from E. coli contains a mixture of monomer (15 kDa), dimer (30 kDa), and multimers. The dimer is an active polypeptide chain containing 2X142 amino acid residues.

4911 | BMP-6 human recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: VGR, VGR1, BMP-6

Alternates names: Scatter Factor (SF), Hepatopoietin (HPTA), HGF, HGFB, F-TCF

Taglines: Induces all osteogenic markers in mesenchymal stem cells.

NCBI Gene ID #: 3082

NCBI Gene Symbol: HGF

Gene Source: Human

Accession #: P14210

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: The ED determined by the scattering activity in the MDCK cell assay is typically at 0.5-1.0 ng/ml.

Results: 2-12 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 78.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.5-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A