Description
BMP-7 Antibody [M123-11A] | 38-232 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: BMP-7 antibody is produced in mice using highly pure (>98%) recombinant human BMP-7 as the immunizing antigen.
Research Area: Signal Transduction, Growth Factors
Tested Application: E
Application: ELISA:
In a sandwich ELISA (assuming 100 μL/well) , when used as a capture antibody at a concentration of 2.0-4.0 μg/mL, this antibody will detect at least 100 pg/mL of recombinant human BMP-7/OP-1 when used with our biotinylated antigen affinity purified-hBMP-7 as the detection antibody at a concentration of approximately 0.5-1.0 μg/mL.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: This IgG1K antibody was purified from cell culture by Protein G affinity chromatography.
Clonality: Monoclonal
Clone: M123-11A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Lyophilized
Buffer: N/A
Concentration: N/A
Storage Condition: BMP-7 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚C when reconstituted.
Alternate Name: OP-1, Bone morphogenetic protein, OP1, Bone morphogenetic protein 7, Osteogenic protein 1, BMP-7, OP-1
User Note: Centrifuge vial prior to opening.
BACKGROUND: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.