BMP-8B (Mouse) ELISA Kit | E5097-100

BMP-8B (Mouse) ELISA Kit | E5097-100

Description: Bone morphogenetic protein 8B (BMP-8B) belongs to the transforming growth factor-β (TGF-β) signaling family and has a very broad biological role in development. It plays an essential role in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. It induces cartilage and bone formation. BMP-8B may be the osteo-inductive factor responsible for the phenomenon of epithelial osteogenesis. It plays a role in calcium regulation and bone homeostasis. BMP-8B is a major contributor to NASH progression. Absence of BMP8B in healthy livers, inhibition of BMP-8B may represent a promising new therapeutic avenue for NASH treatment. BMP-8B, a previously unknown secreted factor in cancer progression, has the potential to be used as a prognostic biomarker. ’s BMP-8B (Mouse) ELISA Kit is based on the Sandwich-ELISA principle. The micro-ELISA plate provided in this kit has been pre-coated an antibody specific to Mouse BMP-8B. Standards or samples are added to the micro-ELISA plate wells that bind to the specific antibody. Then a biotinylated detection antibody specific for Mouse BMP-8B and Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. The wells are washed, a TMB substrate solution is added to the wells and blue color develops in proportion to the amount of BMP-8B bound. The enzyme-substrate reaction is terminated by the addition of stop solution and turns color. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Mouse BMP-8B. The concentration of Mouse BMP-8B in the samples can be calculated by comparing the OD of the samples to the standard curve.

Alternate Name: BMP-8B ELISA Kit; BMP-8 ELISA Kit; BMP8BMP-8B ELISA Kit; bone morphogenetic protein 8 ELISA Kit; osteogenic protein 2 ELISA Kit; bone morphogenetic protein 8b ELISA Kit; dJ118J21.1 ELISA Kit; bone morphogenetic protein 8 ELISA Kit; osteogenic protein 2 ELISA Kit; MGC131757 ELISA Kit; OP2 ELISA Kit; OP-2 ELISA Kit; Osteogenic protein 2 ELISA Kit

Tag Line: A highly sensitive sandwich ELISA kit for the quantitative measurement of BMP-8B

Summary: N/A

Detection Method: Absorbance is measured at 450 nm

Sample Type: Serum, Plasma, Tissue lysates and other biological fluids

Species Reactivity: Mouse

Applications: The ELISA kit is used for the quantitative detection of BMP-8B in serum, plasma, tissue homogenates and other biological fluids

Features & Benefits: Recovery Rate: 87-103% for serum, 85-104% for EDTA plasma and 92-103% for heparin plasma Detection range: 15.625-1000 pg/ml Sensitivity: 9.375 pg/ml Highly sensitive and specific Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10%