763

BMP2 Monoclonal Antibody | E-AB-70352

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SKU:
763-E-AB-70352-GEN
NULL307.00 - NULL593.00

Description

BMP2 Monoclonal Antibody | E-AB-70352 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: BDA2, BMP-2, BMP-2A, Bmp2, BMP2, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A

Application: IHC

Reactivity: Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Background: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Concentration: 2.65 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein corresponding to Mouse BMP2

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:200-1:800

Clone: 2H6D12

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A

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