BMPR2 Polyclonal Antibody | E-AB-40197

BMPR2 Polyclonal Antibody | E-AB-40197 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: BMP type II receptor, BMP type-2 receptor, BMPR 2, BMPR 3, BMPR II, BMPR-2, BMPR-II, Bmpr2, BMPR2, BMPR3, BMPRII, BMR 2, BMR2, Bone morphogenetic protein receptor type 2, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, Bone morphogenic protein receptor type II serine threonine kinase, BRK 3, BRK3, PPH 1, PPH1, Serine threonine kinase type II activin receptor like kinase, T ALK, TALK, Type II activin receptor like kinase

Application: WB

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Background: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Rat Bone morphogenetic protein receptor type-2 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 60 kDa

Molecular Weight(Observed): 60 kDa