BMS-663068 | B2299

BMS-663068 (Fostemsavir) is a potent HIV-1 attachment inhibitor. Fostemsavir is a prodrug of the small-molecule inhibitor BMS-626529 (Cat. No. B1557) which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.

BMS-663068 (Fostemsavir) is a potent HIV-1 attachment inhibitor. Fostemsavir is a prodrug of the small-molecule inhibitor BMS-626529 (Cat. No. B1557) which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.

B2299 | BMS-663068 DataSheet

Alternate Name/Synonyms: (3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl)methyl dihydrogen phosphate; Fostemsavir

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 864953-29-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₆N₇O₈P

Molecular Weight: 583.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent HIV-1 attachment inhibitor

MDL Number: N/A

PubChem CID: 11319217

SMILES: CC1=NN(C=N1)C2=NC=C(C3=C2N(C=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)COP(=O)(O)O)OC

InChi: InChI=1S/C25H26N7O8P/c1-16-27-14-32(28-16)23-21-20(19(39-2)12-26-23)18(13-31(21)15-40-41(36,37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17/h3-7,12-14H,8-11,15H2,1-2H3,(H2,36,37,38)

InChi Key: SWMDAPWAQQTBOG-UHFFFAOYSA-N