BOD1 Polyclonal Antibody | E-AB-16283

BOD1 Polyclonal Antibody | E-AB-16283 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Biorientation defective 1, Biorientation defective protein 1, biorientation of chromosomes in cell division 1, Biorientation of chromosomes in cell division protein 1, BOD1, BOD1, FAM44B, family with sequence similarity 44, member B, Protein FAM44B

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell biology, Epigenetics and Nuclear Signaling

Background: Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human BOD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A