Description
Bohemine is a potent and selective, cell-permeable, cyclin-dependent kinase (CDK) inhibitor IC₅₀ = 1 µM). Arrests cell cycle in the G/S boundary and activates mature bovine oocytes. Bohemine is structurally similar to Olomoucine and Roscovitine (Cat. No.1950).
Bohemine is a potent and selective, cell-permeable, cyclin-dependent kinase (CDK) inhibitor IC₅₀ = 1 µM). Arrests cell cycle in the G/S boundary and activates mature bovine oocytes. Bohemine is structurally similar to Olomoucine and Roscovitine (Cat. No.1950).
Alternate Name/Synonyms: 3-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl)amino)propan-1-ol
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 189232-42-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₂₄N₆O
Molecular Weight: 340.43
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective, cell-permeable, cyclin-dependent kinase (CDK) inhibitor
MDL Number: MFCD04974145
PubChem CID: 2422
SMILES: CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCCO
InChi: InChI=1S/C18H24N6O/c1-13(2)24-12-21-15-16(20-11-14-7-4-3-5-8-14)22-18(23-17(15)24)19-9-6-10-25/h3-5,7-8,12-13,25H,6,9-11H2,1-2H3,(H2,19,20,22,23)
InChi Key: OPQGFIAVPSXOBO-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |