Bostrycin | B2128

Bostrycin is a tetrahydroanthraquinone isolated from Bostrychonema aloestre. It induces mitochondria-mediated apoptosis in the yeast saccharomyces cerevisiae, inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway. It also displays activity against Myobacterium tuberculosis protein tyrosine phosphatase (MptpB) in vitro.

Bostrycin is a tetrahydroanthraquinone isolated from Bostrychonema aloestre. It induces mitochondria-mediated apoptosis in the yeast saccharomyces cerevisiae, inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway. It also displays activity against Myobacterium tuberculosis protein tyrosine phosphatase (MptpB) in vitro.

B2128 | Bostrycin DataSheet

Alternate Name/Synonyms: (5R,6R,7S)-5,6,7,9,10-pentahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione; Rhodosporin

Appearance: Dark red solid

Formulation: N/A

CAS Number: 21879-81-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₆O₈

Molecular Weight: 336.3

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (1 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An antibacterial agent

MDL Number: N/A

PubChem CID: 30839

SMILES: CC1(CC2=C(C3=C(C(=O)C=C(C3=O)OC)C(=C2C(C1O)O)O)O)O

InChi: InChI=1S/C16H16O8/c1-16(23)4-5-8(14(21)15(16)22)13(20)9-6(17)3-7(24-2)12(19)10(9)11(5)18/h3,14-15,18,20-23H,4H2,1-2H3/t14-,15-,16+/m1/s1

InChi Key: ZQNOLGRKZRDRQO-OAGGEKHMSA-N