BP-1 Antibody [FG35.4] (Biotin) | 98-888

BP-1 Antibody [FG35.4] (Biotin) | 98-888 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Obesity

Tested Application: Flow

Application: BP-1 Antibody [FG35.4] for use in flow cytometry assays.

Specificiy: BP-1

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [FG35.4]

Isotype: IgG1

Conjugate: Biotin

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Ly-51, 6C3, aminopeptidase A, glutamyl aminopeptidase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.