BPGM Polyclonal Antibody | E-AB-18543

BPGM Polyclonal Antibody | E-AB-18543 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2, 2, 3-bisphosphoglycerate mutase, 2, 3-bisphosphoglycerate mutase, erythrocyte, 2, 3-bisphosphoglycerate synthase, 2, 3-diphosphoglycerate mutase, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, Ab2 098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG dependent PGAM, BPG-dependent PGAM, Bpgm, C86192, DPGM, Erythrocyte 2, 3 bisphosphoglycerate mutase, erythrocyte, PMGE

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal transduction

Background: 2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Concentration: 1.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 30 kDa

Molecular Weight(Observed): Refer to figures