BPI polyclonal Antibody | BS90144

BPI polyclonal Antibody | BS90144 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, zebrafish

Application: WB FC

Application Range: WB:1:1,000-1:2,000 FC:1:50-1:100

Background: The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules) . The 31.5-kb-long human BPI gene maps to chromosome 20q11.23-q12, contains 15 exons, and encodes a 456 amino acid protein. Epithelial cells which line mucosal surfaces are the first line of defense against bacterial invasion and infection. BPI localizes to the cell surface of epithelial cells and blocks endotoxin-mediated signaling, thereby protecting mucosal surfaces against gram-negative bacteria and their endotoxin. BPI, lipopolysaccharide binding protein (LBP), phospholipid transfer protein (PLTP), and cholesteryl ester transfer protein (CETP) constitutes a family of functionally related proteins.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: BPI polyclonal Antibody detects endogenous levels of BPI protein.

Molecular Weight: 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BPI, Bactericidal permeability-increasing protein, bactericidal/permeability-increasing protein, BPI, BPI fold containing family D, member 1, BPIFD1, CAP 57, rBPI, recombinant BPI holoprotein, rBPI,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: