Brachyury polyclonal Antibody | BS90145

Brachyury polyclonal Antibody | BS90145 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB IHC FC IP

Application Range: WB:1:500 IHC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50

Background: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. Genetic variations in T are associated with susceptibility to neural tube defects (NTD) . NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis.

Storage & Stability: Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Specificity: Brachyury polyclonal Antibody detects endogenous levels of Brachyury protein.

Molecular Weight: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TBXT, BRAC, Brachyury homolog, Brachyury protein, Bry, MGC104817, Protein T, SAVA, T, T brachyury homolog, T brachyury transcription factor, T Protein, T, brachyury homolog (mouse), TFT, Transcription factor T Antibody

Immunogen: Recombinant protein within human Brachyury/ Bry aa 200-400.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A purified.

Pathway: