BRAF V600E Antibody (C-Term) [APR33629G]

BRAF V600E Antibody (C-Term) [APR33629G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 576-606 amino acids from human.

Cellular Localisation: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.

Molecular Weight: 84437

Clone: Polyclonal

Gene Name: BRAF (HGNC:1097)

Gene ID: 673

Function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable) . Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126) . May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179) .

Summary: Tissue Location: Brain and testis.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC-P

Dilution: IHC-P--1:100~500 WB--1:2000

Synonyms: Serine/threonine-protein kinase B-raf, 2.7.11.1, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1