400

BRCA1 Antibody (pSer1524)

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SKU:
400-SPC-1354D-GEN
Availability:
IN STOCK
NULL599.00

Description

Rabbit Anti-Human BRCA1 (pSer1524) Polyclonal

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Additional Information

Size:
100 µl
Target:
BRCA1 (pSer1524)
Conjugate:
Unconjugated
Research Area:
Cell Signaling | Epigenetics and Nuclear Signaling | DNA/RNA | DNA Damage and Repair | BRAC1 | Cell Signaling | Epigenetics and Nuclear Signaling | Chromatin Modifying Enzymes | Chromatin Ubiquitination | Cell Signaling | Post-translational Modificat
Alternative Name:
BRCAI Antibody, EC:2.3.2.27 Antibody, BRCA 1 Antibody, BRCC1 Antibody, Protein phosphatase 1 regulatory subunit 53 Antibody, BRCA1 Antibody, BRCA1 DNA repair associated Antibody, FANCS Antibody, PPP1R53 Antibody, PNCA4 Antibody, Breast cancer type 1
Category:
Antibodies
Product Type:
Polyclonal Antibody
Immunogen:
Synthetic phospho-peptide from human BRCA1 around the phosphorylation site of serine 1524 (pSer1524).
Immunogen Species:
Human
Applications:
IHC, ELISA
Host:
Rabbit
Isotype:
N/A
Species Reactivity:
Human
Antibody Dilution:
IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user.
Purification:
Peptide Affinity Purified
Storage Buffer:
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
Concentration:
N/A
Specificity:
Detects endogenous levels of BRCA1 protein only when phosphorylated at serine 1524 (pSer1524). Detects a band at ~207 kDa.
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
N/A
Cellular Localization:
Nucleus, Chromosome, Cytoplasm, Chromosome, Cytoskeleton, Gamma-Tubulin Ring Complex, Brca1-A Complex, Brca1-Bard1 Complex, Lateral Element, Nucleoplasm, Plasma Membrane, Intracellular Ribonucleoprotein Complex, Protein Complex, Ubiquitin Ligase Comp
Tissue Specificity:
Isoform 1 and isoform 3 are widely expressed. Isoform 3 is reduced or absent in several breast and ovarian cancer cell lines.
Accession Number:
NP_009225.1
Gene ID:
672
Swiss-Prot:
P38398
Field of Use:
For in vitro research use only.
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